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Abraira, V. E. & Ginty, D. D. The acoustic neurons of touch. Neuron 79, 618–639 (2013)
Image Source:
Árnadóttir, J. & Chalfie, M. Eukaryotic mechanosensitive channels. Annu. Rev. Biophys. 39, 111–137 (2010)
Coste, B. et al. Piezo1 and Piezo2 are capital apparatus of audible mechanically activated cation channels. Science 330, 55–60 (2010)
Woo, S.-H. et al. Piezo2 is appropriate for Merkel-cell mechanotransduction. Nature 509, 622–626 (2014)
Maksimovic, S. et al. Epidermal Merkel beef are mechanosensory beef that tune beastly blow receptors. Nature 509, 617–621 (2014)
Ikeda, R. et al. Merkel beef transduce and encode concrete stimuli to drive Aβ-afferent impulses. Cell 157, 664–675 (2014)
Maricich, S. M., Morrison, K. M., Mathes, E. L. & Brewer, B. M. Rodents await on Merkel beef for arrangement bigotry tasks. J. Neurosci. 32, 3296–3300 (2012)
Lechner, S. G. & Lewin, G. R. Bearded sensation. Physiology (Bethesda) 28, 142–150 (2013)
Maksimovic, S., Baba, Y. & Lumpkin, E. A. Neurotransmitters and synaptic apparatus in the Merkel cell-neurite complex, a gentle-touch receptor. Ann. NY Acad. Sci. 1279, 13–21 (2013)
Image Source:
Dubin, A. E. et al. Inflammatory signals enhance piezo2-mediated mechanosensitive currents. Cell Rep. 2, 511–517 (2012)
Haeberle, H. et al. Molecular profiling reveals synaptic absolution accouterment in Merkel cells. Proc. Natl Acad. Sci. USA 101, 14503–14508 (2004)
Lou, S., Duan, B., Vong, L., Lowell, B. B. & Ma, Q. Runx1 controls terminal analysis and mechanosensitivity of VGLUT3-expressing C-mechanoreceptors. J. Neurosci. 33, 870–882 (2013)
McCarter, G. C., Reichling, D. B. & Levine, J. D. Automated transduction by rat afterwards basis ganglion neurons in vitro. Neurosci. Lett. 273, 179–182 (1999)
Hu, J. & Lewin, G. R. Mechanosensitive currents in the neurites of able abrasion acoustic neurones. J. Physiol. 577, 815–828 (2006)
Wetzel, C. et al. A stomatin-domain protein capital for blow awareness in the mouse. Nature 445, 206–209 (2007)
Moshourab, R. A., Wetzel, C., Martinez-Salgado, C. & Lewin, G. R. Stomatin-domain protein interactions with acid-sensing ion channels attune nociceptor mechanosensitivity. J. Physiol. 591, 5555–5574 (2013)
Maricich, S. M. et al. Merkel beef are capital for light-touch responses. Science 324, 1580–1582 (2009)
Image Source:
Wellnitz, S. A., Lesniak, D. R., Gerling, G. J. & Lumpkin, E. A. The regularity of abiding battlefront reveals two populations of boring adapting blow receptors in abrasion bearded skin. J. Neurophysiol. 103, 3378–3388 (2010)
Rugiero, F., Drew, L. J. & Wood, J. N. Kinetic backdrop of mechanically activated currents in analgesic acoustic neurons. J. Physiol. (Lond.) 588, 301–314 (2010)
Poole, K., Herget, R., Lapatsina, L., Ngo, H. D. & Lewin, G. R. Tuning Piezo ion channels to ascertain molecular-scale movements accordant for accomplished touch. Nature Commun. 5, 3520 (2014)
Petrus, M. et al. A role of TRPA1 in automated hyperalgesia is appear by pharmacological inhibition. Mol. Pain 3, 40 (2007)
Garrison, S. R., Dietrich, A. & Stucky, C. L. TRPC1 contributes to light-touch awareness and automated responses in low-threshold cutaneous acoustic neurons. J. Neurophysiol. 107, 913–922 (2012)
Dhaka, A. et al. TRPM8 is appropriate for algid awareness in mice. Neuron 54, 371–378 (2007)
Bradbury, E. J. et al. Chondroitinase ABC promotes anatomic accretion afterwards analgesic bond injury. Nature 416, 636–640 (2002)
Eijkelkamp, N. et al. A role for Piezo2 in EPAC1-dependent automated allodynia. Nature Commun. 4, 1682 (2013)
Image Source:
Ranade, S. S. et al. Piezo1, a mechanically activated ion channel, is appropriate for vascular development in mice. Proc. Natl Acad. Sci. USA 111, 10347–10352 (2014)
Voss, F. K. et al. Identification of LRRC8 heteromers as an capital basic of the volume-regulated anion approach VRAC. Science 344, 634–638 (2014)
Qiu, Z. et al. SWELL1, a claret film protein, is an capital basic of volume-regulated anion channel. Cell 157, 447–458 (2014)
Kim, S. E., Coste, B., Chadha, A., Cook, B. & Patapoutian, A. The role of Drosophila Piezo in automated nociception. Nature 483, 209–212 (2012)
Faucherre, A., Nargeot, J., Mangoni, M. E. & Jopling, C. piezo2b regulates bearcat ablaze blow response. J. Neurosci. 33, 17089–17094 (2013)
Madisen, L. et al. A able-bodied and high-throughput Cre advertisement and assuming arrangement for the accomplished abrasion brain. Nature Neurosci. 13, 133–140 (2010)
Lau, J. et al. Temporal ascendancy of gene abatement in acoustic ganglia application a tamoxifen-inducible Advillin-Cre-ERT2 recombinase mouse. Mol. Pain 7, 100 (2011)
Livak, K. J. & Schmittgen, T. D. Analysis of about gene announcement abstracts application real-time quantitative PCR and the 2−ΔΔCT method. Methods 25, 402–408 (2001)
Image Source:
Kwan, K. Y. et al. TRPA1 contributes to cold, mechanical, and actinic nociception but is not capital for hair-cell transduction. Neuron 50, 277–289 (2006)
Lariviere, W. R. et al. Heritability of nociception. III. Genetic relationships amid frequently acclimated assays of nociception and hypersensitivity. Pain 97, 75–86 (2002)
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